TARGETING ALDOSTERONE

Not all hypertension is the same...
Aldosterone may be to blame.[1a],[2a]

TARGETING ALDOSTERONE

Not all hypertension is the same...
Aldosterone may be to blame.[1a],[2a]

ALDOSTERONE DYSREGULATION drives excessive aldosterone production, making HTN hard to control with standard therapy[1c],[2c],[3a]

Aldosterone plays a key role in the RAAS pathway, helping regulate BP through sodium and water balance[4]

When dysregulated, aldosterone acts independently of RAAS, sustaining high BP despite low renin and high sodium[2d],[5a]

Excess aldosterone also promotes inflammation and fibrosis of the heart, vasculature, and kidneys, leading to end-organ damage independent of BP[3b],[6],[7]

Aldosterone dysregulation is excessive aldosterone production
despite low renin and high sodium balance.[2e],[5b]

Could TARGETING ALDOSTERONE
production offer a potential solution for 

patients with hard-to-control hypertension?[8],[9]

Aldosterone dysregulation is an underlying, underrecognised cause of hypertension and its consequences.[2f]

Current options play a role in the management of hypertension, but there are patients who are not able to reach their BP goal.[10]

SEE WHY

AstraZeneca is committed
to driving awareness of
hard-to-control hypertension,
education, and investigating novel
scientific approaches.

Want the latest information about aldosterone dysregulation
and its link to hypertension?

Subscribe Now